What is depression?

Everyone has hard days. Feeling sad, tired, or discouraged is part of being human. When you feel stuck in sadness and struggle to find motivation, it might be time to talk with someone about how you are feeling.

Depression is a mood disorder that affects how you think, feel, and manage daily life. It doesn’t mean something is “wrong” with you—it means your mind and body need care, just like when you’re sick or injured. The positive news is that clinical depression is treatable, and with help, you can feel better again.

Types of depression

Depression looks and feels different for everyone. Understanding which type you may be experiencing helps you and your health care provider create the right treatment plan. The examples below range from mild, short-term forms of depression to more severe types.

Situational depression

Situational depression is a short-term form of depression that occurs following a stressful life event, such as divorce, retirement, job loss, or the death of a loved one. Symptoms often improve with time, support, and coping strategies.

Seasonal Affective Disorder (SAD)

SAD is a form of depression that typically appears in the fall and winter, when daylight hours are shorter. You may notice fatigue, a decreased interest in spending time with others, changes in sleep patterns or appetite, and feelings of hopelessness. Learn more about SAD (PDF).

Persistent Depressive Disorder (PDD)

PDD (also known as dysthymia) is defined by milder depression symptoms that last for two years or more. Some symptoms may be similar to major depression, though they usually change in intensity or feel milder over time.

Major Depressive Disorder (MDD)

MDD occurs when feelings of sadness, hopelessness, or loss of interest in activities you once enjoyed last for two weeks or more. Health care providers diagnose major depression when you have multiple symptoms that persist and interfere with your daily life.

Melancholic depression

Melancholic depression is when you experience an almost total loss of pleasure or joy in life. You might feel deep despair or emptiness. Your movements or speech may slow noticeably. Symptoms often feel worse in the morning and may include loss of appetite and weight loss.

Perinatal depression

Perinatal depression (also known as postpartum depression) is a form of major depression during pregnancy or within one year after giving birth. It’s common to feel emotional ups and downs after having a baby. When those feelings persist or intensify, it could be a sign of perinatal depression.

Psychotic depression

Psychotic depression happens when depression occurs with psychosis, such as believing things that aren’t true (delusions) or seeing or hearing things that aren’t real (hallucinations). These symptoms can be alarming, but treatment can help.

Treatment-Resistant Depression (TRD)

Treatment-resistant depression occurs when depression doesn't fully improve after common treatments like medication or therapy. Recovery is possible. You may need a combination of treatments or newer approaches.


Causes & risk factors

While the exact causes of depression aren’t fully understood, research shows that depression, bipolar disorder, and related illnesses often result from a combination of genetic, biological, and environmental factors.

Personal factors

  • Brain chemistry: Changes in how certain brain chemicals work may play a role in depression.
  • Personality: People who are highly self-critical, perfectionistic, or have low self-esteem may be more likely to develop depression.
  • Medical illness: Coping with a serious or chronic illness can lead to depression.
  • Substance use: Alcohol and drug use can both cause and worsen depression. Some prescription medications may also contribute to symptoms.
  • Family history: Having a close relative with depression can increase your genetic risk.

Life circumstances

  • Long-term stress: Ongoing problems, like relationship conflict or job stress, can lead to depression over time.
  • Major life changes: Events such as divorce, job loss, or even positive transitions like marriage can trigger depression in people who are already vulnerable.
  • Trauma and grief: Abuse, neglect, or the loss of a loved one can increase the risk of depression. Early trauma, including childhood abuse or exposure to violence, can have lasting effects on mental health.

Signs & symptoms of depression

Depression looks different for everyone. Adults may exhibit signs and symptoms of depression ranging from feelings, thoughts and behaviors. These symptoms can shift in severity over time. 

It’s normal to experience some signs and symptoms occasionally. Providers diagnose depression when several symptoms appear together and interfere with daily living.

Feelings

  • Guilt
  • Hopelessness or sadness
  • Loss of interest in friends, family, and favorite activities
  • Moodiness

Thoughts

  • “I’m a burden.”
  • “I’m a failure.”
  • “I’m worthless.”
  • Delusions or hallucinations
  • Thoughts of self-harm
  • Trouble concentrating
  • Trouble remembering

Behaviors

  • Attempts to harm yourself
  • Changes in appetite
  • Changes in sleep
  • Digestive problems
  • Headaches
  • Missing work, school, or other commitments
  • Physical problems
  • Sexual problems
  • Substance abuse
  • Tiredness or lack of energy
  • Unexplained aches and pains
  • Weight gain
  • Weight loss
  • Withdrawing from people

Symptoms in children and adolescents

  • Aggression
  • Alcohol or drug use
  • Anger
  • Behavior changes
  • Changes in appetite or eating habits
  • Conflict with authority
  • Declining grades
  • Excessive crying
  • Headaches
  • Intense sensitivity to rejection
  • Irritability and withdrawal
  • Isolation and hopelessness
  • Loss of interest in activities they used to enjoy
  • Low energy
  • Sleep problems
  • Stomach aches
  • Thoughts of suicide

When to seek help for depression

If you’ve experienced five or more symptoms of depression for two weeks or longer, talk to your doctor or a health care professional. They follow guidelines to assess symptoms such as ongoing sadness, loss of interest, mood changes, and difficulty managing daily life. 

Only a licensed health care professional can diagnose clinical depression. With their support, you can better understand what you’re feeling and begin a treatment plan that supports your mental health.


Who depression affects

Anyone can develop depression. How it feels and shows up varies from person to person.

Women & depression

Depression affects women about twice as often as men, with nearly 1 in 4 women experiencing it at some point in life. This difference exists across all racial, ethnic, and economic backgrounds.

Women may be more likely to experience depression at certain times:

  • During pregnancy
  • After giving birth
  • During menopause
  • During different phases of the menstrual cycle

Depression in women often occurs alongside anxiety or eating disorders.

Men & depression

About 1 in 7 men experience depression at some point in life.

Oftentimes, men view depression as a sign of weakness and something they should manage on their own. This can make them less likely to talk about what they’re feeling, leading to undiagnosed or untreated depression.

Common signs of depression in men include:

  • Focusing on physical symptoms such as fatigue, pain, or sleep problems
  • Showing irritability or anger more often than sadness
  • Using alcohol or drugs to cope with difficult emotions

Children & adolescents

Depression affects about 11% of adolescents and occurs most often between ages 15 and 24. Roughly 3% of children experience severe symptoms. After puberty, girls are nearly twice as likely as boys to develop depression.

Some young people face a higher risk of developing depression, especially those with:

  • ADHD, behavioral, eating, or anxiety disorders
  • Developmental or intellectual disabilities
  • Chronic medical conditions such as diabetes, asthma, or cancer

Depression during adolescence can affect healthy development. It’s often linked to substance use, relationship challenges, lower school performance, and an increased risk of suicide. Teens who experience depression are also more likely to face it as adults.

Depression in different age groups and communities

College students

College students have much higher rates of depression than the general population. Nearly 1 in 3 students report having trouble functioning due to depression. Unfortunately, many students try to hide or ignore symptoms due to social or academic pressure.

Several factors can contribute to depression during college, including:

  • Forming new relationships
  • Greater access to alcohol and drugs
  • Irregular sleep
  • Major life transitions (leaving home, living independently)
  • Peak onset age (15–24) coincides with college years

Visit the Healthy Minds Study for current data on college student mental health.

Older adults

Up to 20% of older adults experience depression, with even higher rates in nursing homes. Depression can be harder to recognize in older adults for several reasons:

  • Older adults are more likely to notice physical symptoms than emotional ones.
  • Depression increases the risk of cognitive decline in older adults.
  • Depression can worsen other disabilities and increase mortality.
  • Symptoms may be confused with dementia, stroke, or other conditions common in older populations.
  • Fear of stigma can make it harder for older adults to open up about their feelings or ask for help.
LGBTQIA+ people

Lesbian, gay, bisexual, transgender, and queer people have higher rates of depression, suicide, and self-harm than the general population. Research shows this is mainly due to discrimination, prejudice, stress, and abuse.

If you need a safe, understanding place to turn to, The LGBTQ+ National Help Center and The Trevor Project are ready to help.

People of color

Mental health stigma and systemic barriers can make it harder for people in communities of color to get the care they deserve. Factors such as poverty, discrimination, and negative stereotypes can take a toll on well-being. Research shows that Black adults are about 20% more likely to experience severe psychological distress than white adults.

People of color often face additional challenges when seeking mental health care, including:

  • Discrimination in treatment settings
  • Lack of culturally competent care
  • Language barriers
  • Less access to mental health services
  • Less likely to receive treatment
  • Lower rates of health insurance
  • More stigma around mental health
  • Poorer quality of care when they do receive it

Resources & tools

Depression Self-Check Tool (PDF)

Depression Self-Check Tool (PDF)

Wondering if you might have depression? Take this 2-minute quiz to understand your symptoms and find support.


Choosing a Therapist (PDF)

Choosing a Therapist (PDF)

Explore tips for finding a therapist who meets your needs and helps you feel comfortable during treatment.

Preparing For Your Appointments (PDF)

Preparing For Your Appointments (PDF)

Are you ready to speak with a professional? Use this guide to help organize your thoughts and feelings.


Need help right now?

Call or text the Suicide and Crisis Lifeline at 988 to talk with trained counselors, available 24/7. Support is available whenever you need it. 

Get help now

Depression & other medical conditions

Depression often occurs alongside other medical conditions. Discover how it interacts with both acute and chronic conditions, ranging from heart disease to sleep disorders.

Learn about the connection

Stages of depression recovery

Depression recovery is a gradual process that happens in stages. Understanding each stage can help you track your progress and stay on course.

Learn the Stages

Frequently asked questions

How common is depression?

According to the World Health Organization (WHO), depression affects about 1 in 5 women and 1 in 10 men worldwide at some point in their lives. In the U.S., an estimated 22% of women and 14% of men between the ages 18 and 64 will experience depression at some point in their lifetime.

Who is most affected by depression?

Depression doesn't discriminate. Men and women of every age, race, ethnicity, educational level, and social and economic background experience depression. The problems that result from depression often get worse because most people with depression are never diagnosed, let alone treated.

When is the best time to get treatment for depression?

When you identify and treat depression early, symptoms are manageable. There are numerous practical strategies for managing the condition. Talk with a health care provider to learn what’s best for you.

How long does depression last?

The duration and intensity of depression vary from person to person. Symptoms are generally classified as:

  • Mild: Less intrusive symptoms go away on their own after a short period of time
  • Moderate: Intrusive symptoms affecting your mood, productivity, and ability to focus can persist for 6 months or longer without treatment
  • Severe: Intense symptoms disrupting your daily life beyond the basics can last 6 months or longer
How do I know if I'm just sad or actually depressed?

Everyone experiences sadness occasionally. Depression, however, is more intense, lasts longer (typically weeks or more), and disrupts daily activities.

If you're wondering whether what you're experiencing is depression, the PHQ-9 screening tool can help you explore your symptoms. While it’s not an official diagnosis, it's a good starting point for understanding what you're feeling.

What should I do if I think I have depression?

If you think you have depression, talk to your health care provider. They can evaluate your symptoms, rule out other medical conditions, and discuss treatment options with you. Seeking help is a brave and important step.

References

Avenevoli, S., Swendsen, J., He, J. P., Burstein, M., & Merikangas, K. R. (2015). Major depression in the National Comorbidity Survey—Adolescent Supplement: prevalence, correlates, and treatment. Journal of the American Academy of Child & Adolescent Psychiatry, 54(1), 37-44.

Bailey R.K., Mokonogho J., Kumar A. (2019). Racial and ethnic differences in depression: current perspectives. Neuropsychiatric disease and treatment, 603-609.

Bostwick, W. B., Boyd, C. J., Hughes, T. L., West, B. T., & McCabe, S. E. (2014). Discrimination and mental health among lesbian, gay, and bisexual adults in the United States. American Journal of Orthopsychiatry, 84(1), 35-45.

Desch, J., Mansuri, F., Tran, D., Schwartz, S. W., & Bakour, C. (2023). The association between adverse childhood experiences and depression trajectories in the Add Health study. Child abuse & neglect, 137, 106034.

Goodwin, R.D., Dierker, L.C., Wu, M., Galea, S. Hoven, C.W., & Weinberger, A.H. (2022). Trends in US depression prevalence from 2015 to 2020: the widening treatment gap. American Journal of Preventative Medicine, 63(5), 726-733.

Hu T., Zhao X., Wu M., Li Z., Luo L., Yang C., & Yang F. (2022). Prevalence of depression in older adults: a systematic review and meta-analysis. Psychiatry Research, 311.

Lam, R. W., McIntosh, D., Wang, J., Enns, M. W., Kolivakis, T., Michalak, E. E., ... & Milev, R. V. (2016). Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 1. disease burden and principles of care. The Canadian Journal of Psychiatry, 61(9), 510-523.

Martin, Lisa & W Neighbors, Harold & Griffith, Derek. (2013). The experience of symptoms of depression in men vs women: analysis of the National Comorbidity Survey Replication. JAMA Psychiatry 70: 1100-1106.

Miller L. & Campo J.V. (2021) Depression in adolescents. New England Journal of Medicine, 385(5), 445-449.

National Institute of Mental Health. (2024). Depression. Retrieved on September 10, 2024 from https://www.nimh.nih.gov/health/topics/depression/index.shtml.

O'Shea J., Jenkins R., Nicholls D., Downs J., & Hudson L.D. (2024). Prevalence, severity and risk factors for mental disorders among sexual and gender minority young people: a systematic review of systematic reviews and meta-analyses. European Child & Adolescent Psychiatry, 1-24.

Sheldon E., Simmonds-Buckley M., Bone C., Mascarenhas T., Chan N., Wincott M., ... & Barkham M. (2021). Prevalence and risk factors for mental health problems in university undergraduate students: A systematic review with meta-analysis. Journal of affective disorders, 287, 282-292.

Shorey S., Ng E.D., & Wong C.H. (2022). Global prevalence of depression and elevated depressive symptoms among adolescents: A systematic review and meta-analysis. British Journal of Clinical Psychology, 61(2), 287-305.