Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed) - PAR-25-060
Funder
National Institutes of Health
LOI Required
No
Application Deadline
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Funding Amount
$750,000.00
Maximum Project Duration
3 years
Research Focus Areas
Neurobiology/Neuroscience
Pharmacotherapy
Alzheimer’s Disease, Dementia, and Neurocognitive Disorders
Molecular and Cellular
Population Focus
Non-Human Animal Studies
Research Methods
Animal Models
Quantitative Research Methods
Description
This Notice of Funding Opportunity (NOFO) encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal of this NOFO is to promote a significant improvement in the translational relevance of animal models or ex vivo systems that will be utilized to facilitate future development of neurotherapeutics. Models proposed for this NOFO would have the potential to provide feasible and meaningful assessments of efficacy following therapeutic intervention. This NOFO is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) Program focused on enabling the exploratory and early stages of drug discovery.