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Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R01 Clinical Trial Optional) - PAR-25-036

Funder
National Institutes of Health
LOI Required
No
Application Deadline
Maximum Project Duration
5 years
Research Focus Areas
Molecular and Cellular
Neurobiology/Neuroscience
Pharmacotherapy
Research Methods
Randomized Control Trials (RCT)
Magnetic Resonance Imaging (MRI)/Other Imaging
Description
This Notice of Funding Opportunity (NOFO) invites research grant applications that propose the development and evaluation of novel radioligands for positron emission tomography (PET) or single photon emission computed tomography (SPECT) for molecular targets (e.g., receptors, intracellular messengers, disease-related proteins) that are implicated in brain disorders as tools to study disease pathophysiology and/or for assessing target engagement of potential therapeutic candidates.